HPV, Cervical Cancer and Gardasil Fact Sheet
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HPV Infection
• HPV is the most common sexually-transmitted infection in the U.S.
• Most HPV infections cause no symptoms and more than half of all sexually active persons
become infected at some point in their lives.
• There are more than 100 HPV types and 30-40 can be sexually transmitted, with 15 HPV types
associated with cervical cancer.
• The majority of women clear the HPV virus from their bodies naturally but women with risk
factors, such as HIV infection, smoking, long-time use of oral contraceptives, and co-infection with
herpes simplex virus or chlamydia, are at higher risk for chronic HPV infection.
• Chronic HPV infection is associated with precancerous changes in the cervix which can
progress to cervical cancer if left undiagnosed and untreated.
• Between 1955 and 1992, cervical cancer deaths in American women dropped by 74 percent due
to routine pap smears.
• Chronic HPV infections are also associated with other genital cancers, such as anal cancer.
• There are about 9,800 new cases of cervical cancer annually diagnosed in the U.S., which
represents .007 percent out of the approximately 1,372,000 new cancer cases of all types diagnosed.
• In the U.S., cervical cancer is the 14th most common type of cancer in women but in South
America, Africa and Asia, cervical cancer is the most common cancer in women because of poor
health care and no pap screening.
• There are about 3,700 deaths in mostly older American women annually attributed to HPV-related
cervical cancer, which is about .006 percent of the approximately 570,000 cancer deaths that occur in
the U.S.
• Most cervical pre-cancers develop slowly, so nearly all cervical cancers can be prevented with
regular pap smear screening and prompt treatment.
• Survival for women with pre-invasive cervical cancer lesions is nearly 100% with early diagnosis
and appropriate treatment.
What is the effect of the vaccine on HPV infection?
• In the general population the Merck vaccine prevented genital warts that were due to vaccine-
type strains.
• The vaccine prevented human papillomavirus infection with four HPV subtypes in people who
weren't already infected with these types.
• The vaccine did not prevent infection with the HPV types that are not contained in the vaccine.
• HPV disease due to one of the many subtypes NOT included in the vaccine still occurred.
Vaccinated subjects got infected with non-vaccine HPV types at the same rate as non-vaccinated
subjects.
• In subjects who were already infected with a particular vaccine virus type, the vaccine did not
prevent disease due to that type, but it did prevent new disease caused by the other vaccine
subtypes.
• The studies that the drug maker gave to the FDA did not tell if condom use was tracked; this is
very important missing data, since condoms alone are responsible for a 70% reduction in all types of
HPV. The vaccine gives 100% protection against four HPV types and no protection against other HPV
types, whereas condoms give 70% protection against all HPV types.
• Merck has never proved Gardasil prevented cancer, only that it decreased abnormal PAP
smears.
• No one has ever proven HPV causes cancer. In the Merck study the decrease in total pre-
cancerous PAP smears was less than statistically predicted given that Gardasil prevents two HPV
strains. In other words, since Gardasil prevents pre-cancerous PAPs due to types 16 & 18 HPVs, then
the total number of pre-cancerous PAPs should decrease by a commensurate percentage. Simple
enough. It didn’t.
This led an FDA scientist to question the theory that HPV CAUSES cervical cancer. It’s instead
possible that HPV is an “opportunistic infection” that thrives in the presence of cancer cells. It’s a
chicken and egg sort of thing.
Remember, no one has ever proven HPV is the cause of cancer. That assumption was made because
HPV is often – but not always - present with cervical cancer. But again, just because they’re frequent
companions, doesn’t prove one leads to the other.
Safety and Side Effects
The Merck study showed an increase in pre-cancer related to the vaccine types in the people
who already had these infections before they got the vaccine.
The manufacturer also specifies that the vaccine has not been tested to see whether it could
cause cancer. They have not studied the vaccines affects on fertility.
Clinical trials were relatively short with test subjects only being monitored over a period ranging
from 18 months to 4 years, with no data on long-term safety.
There is no evidence concerning the durability of Gardasil's proposed immunity beyond 5 years.
Merck only studied GARDASIL in fewer than 1200 girls under age 16 in pre-licensure trials.
Three deaths due to heart problems and/or blood clotting are seemingly related to the vaccine.
As of May 11, 2007, the 1,637 adverse vaccination reactions reported to the FDA via VAERS
(Vaccine Adverse Event Reporting System) included 371 serious reactions. Of the 42 women who
received the vaccine while pregnant, 18 experienced side effects ranging from spontaneous abortion
to fetal abnormities.
So far more than 40 cases of Guillian-Barre syndrome - a dangerous immune disorder that
causes tingling, numbness and even paralysis of the muscles have been reported in girls who have
received the HPV vaccine.
VAERS is a passive surveillance system and depends upon voluntary reporting of serious health
problems following vaccination. There have been estimates that fewer than 10 percent, even as low
as 1 to 4 percent, of adverse events which occur after prescription drug or vaccine use are ever
reported to government adverse event reporting systems.
Gardasil’s components include aluminium phosphate, sodium chloride, L-histidine, polysorbate
and sodium borate. Exposure to borax may impair fertility or cause damage to an unborn child
Aluminium is implicated as a cause of brain damage, a suspected factor in Alzheimer’s Disease,
dementia, seizures, comas, and allergic skin reactions, and polysorbate is known to cause cancer in
animals.
It is not known if Gardasil will pass into breast milk and what effect that will have.
It is not known if Gardasil effects genes and will thereby effect future generations.
It is not known if Gardasil effects fertility.
Merck says Gardasil should not be given to pregnant women.
Merck was only able to estimate the effectiveness of Gardasil for 5 years. There is no definitive
guideline for it’s effectiveness, tho it doesn’t appear to be once for life.
Political Ties to Merck Lobbyists
Texas Gov. Rick Perry used executive privilege in February to bypass his legislature and
mandate the vaccine in his state for girls entering the sixth grade.
Perry’s chief of staff Deirdre Delisi met with the governor's budget director and three members
of his office for an "HPV Vaccine for Children Briefing" on Oct. 16. That same day, Merck & Co.'s
political action committee donated $5,000 to Perry and a total of $5,000 to eight state lawmakers.
Perry has also received $21,000 from Merck over the years, including $6,000 for his most recent
campaign. According to the San Antonio Express News, Merck also donated $50,000 to a Republican
Governors Association fundraising dinner hosted by Perry. Apparently Merck has donated the same
amount to this dinner annually for the past six years.
Mike Toomey, Perry's former chief of staff and Delisi's predecessor, lobbies for Merck.
According to Delisi's calendar, she met with Toomey three times in the six months before the order
was issued. One meeting happened in August, on the same day two other Perry staffers met with a
different Merck lobbyist for a "Merck HPV Vaccine update."
Delisi is a member of Women In Government. So is Indiana Sen. Connie Lawson, R-Indianapolis,
who introduced a bill that would have required Indiana girls to receive the vaccine. Women In
Government (WIG) has admitted that Merck is a sponsor of the organization. However, both WIG and
Merck have declined to say how much money that sponsorship entails.
In Virginia, for example, Merck, a longstanding contributor to political campaigns in the state,
has spent nearly $40,000 in contributions over the past two years. It has also hired Williams Mullen
Strategies, a prominent lobbying firm, to spearhead the company's efforts to persuade lawmakers in
Richmond to vote for a mandatory vaccine. On the team is Sandra D. Bowen, a well-known Richmond
lobbyist and Cabinet secretary under two governors.
Del. Phil Hamilton, R-Newport reported a donation of $1,000 from Merck just weeks before he
introduced the bill mandating Gardasil. That brings his total from Merck to $10,000 over the past
decade.
Janet Howell, D-Fairfax, sponsor of the Senate companion to Hamilton's bill, landed $500 from
Merck a mere 60 days before she introduced her legislation. Merck had already given Howell $3,500 in
the past 10 years.
In all, Merck has spread around more than a million dollars in the past two election cycles.
Virginia politicians rank fifth among the recipients, landing $13,000 last year.
Newsday has reported that in New York State, Merck laid out more than half a million dollars in
lobbying costs and donations to key officials. Between 1999 and 2006, Merck donated $106,000
($33,400 to Democratic accounts and $72,600 to Republican accounts)
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